Orbital tumors and tumor-like lesions MRI

Title: Orbital tumors and tumor-like lesions MRI Author: Fang Jun fresh Degree-granting units: Tianjin Medical University Keywords: Orbital;; tumor;; hemangioma;; nerve sheath tumor;; lymphangioma;; magnetic resonance imaging Abstract:

 Imaging can not only help clear orbital tumors and tumor-like lesions, but surgery is the treatment plan and the main basis for design in the diagnosis and treatment plays a very important and irreplaceable role. Nevertheless, part of the orbital tumor and tumor-like lesions and differential diagnosis of the preoperative diagnosis was still difficult. Purpose of this Neodymium Magnets study was to explore the magnetic resonance imaging (MRI) scan with enhanced static and dynamic contrast-enhanced scanning in orbital tumor and tumor-like lesions in the diagnosis and differential diagnosis value of three parts.

 A magnetic resonance imaging evaluation of benign and malignant tumors of adult eyes of research

 Objective: prospective study with MRI scan to enhance the static and dynamic contrast-enhanced scans to identify benign and malignant eyes and the value of tumor-like lesions and to assess the performance of MRI to predict which eyes are most likely factor in malignant lesions and two inter-observer consistency.

 Materials and Methods: 102 cases difficult to identify benign and malignant adult orbital soft tissue lesions (male 51 patients, average age 46 years; female 51 patients, average age 54 years) underwent MRI scan, static enhanced scanning and dynamic contrast-enhanced scans. Histopathological lesions were all confirmed. Histopathological evaluation of the results were benign and malignant orbital tumor-like lesions and MRI findings, and using multiple logistic regression analysis and evaluation of orbital malignant lesions predict the most likely performance. Forward-looking assessment of MRI scan, MRI scan enhanced with static and static MRI scan with enhancement and dynamic contrast-enhanced scan three modes subjective diagnosis of benign and malignant lesions of the orbit of sensitivity and specificity.

 Results: 60 cases of benign lesions, 42 were malignant lesions. The two observers, outside the muscle cone and the orbital space before space involvement, shape, border, surrounding the eye disease or other structures, T_1WI signal uniformity, T_2WI signal strength, T_2WI signal uniformity, enhanced mode and dynamic contrast-enhanced curve (TIC) was out of type and other benign and malignant lesions in the eyes there is a significant difference between (p <0. 05). Multivariate logistic regression analysis showed that: the two observers to predict the most likely orbital malignant lesions T2WI showed equal performance is the type of signal and TIC was out of type. http://www.everbeenmagnet.com/en/products/110-sintered-neodymium-magnets Multivariate logistic regression analysis showed that MRI scan enhanced with static and dynamic enhanced MRI of malignant lesions of the orbit prediction sensitivity and specificity were 83.3% and 88.3%, significantly better than the MRI scan (sensitivity and specificity were 78.6% and 86.7%) or MRI scan with a static-enhanced scan (sensitivity and specificity were 78.6% and 88.3%) (p <0.05). Confidence interval using five-point grading (five-point confidence rating scale) subjective diagnosis of benign and malignant eyes, MRI scan enhanced with static and dynamic enhanced MRI sensitivity and specificity were 97.6% and 71.7 %, significantly higher than the MRI scan (sensitivity and specificity were 81% and 58.3%) or MRI scan with a static-enhanced scan (sensitivity and specificity were 81% and 58.3%) (p <0.05).

 Conclusion: MRI scan enhanced with static and dynamic enhanced MRI significantly increased the identification of benign and malignant tumors of adult eyes and the ability of tumor-like lesions. Clear irregular boundary mass lesions surrounding the eye, T_2WI TIC was the type of signal or other type of prompt was out for the malignant lesions, and clear rules of the boundary mass, T_2WI showed low signal, or enhancement pattern was peripheral enhancement was sustained TIC type Enhanced often suggestive of benign lesions.

 Second, magnetic resonance imaging identification of orbital cavernous hemangioma and schwannoma of the value

 Objective: a comparative analysis of orbital cavernous hemangioma and MRI manifestations of nerve sheath tumors, evaluation can help identify both the MRI features.

 Materials and Methods: June 2004 to January 2009, 43 histopathology proven cases of orbital cavernous hemangioma and 16 cases of orbital nerve sheath tumors were treated by MRI scan, static and dynamic enhanced MRI scan enhanced, retrospective comparative analysis both MRI manifestations.

 Results: The lesion location, shape, flatten the eye wall pressure, T_1WI signal and uniformity, T_2WI signal and uniformity, and enhance the scope of the start time to strengthen the whole phase enhancement pattern, TIC type, CI values ​​of the orbital cavernous hemangioma and other nerve sheath tumors and tumors with a significant difference between (p <0. 05).

 Conclusion: Orbital cavernous hemangioma and MRI features of different nerve sheath tumors, contribute to the differential diagnosis. Cavernous hemangioma enhance the performance of the starting point when the sheet to strengthen and "progressive enhancement" is to identify the two most reliable performance.

 Third, the orbital cavernous lymphangioma of the performance of magnetic resonance imaging

 Objective: Analysis of orbital cavernous lymphangioma MRI manifestations.

 Methods: A retrospective analysis of 34 patients (4 males and 30 females, age range is 26 to 66 years, mean age 45 years) were diagnosed as cavernous lymphangioma of the orbit of MRI, cavernous with the control group hemangioma comparison.

 Results: 17 patients (50%) of orbital cavernous lymphangioma occurs in the left side, 17 patients (50%) occurred in the right side; 20 cases (58.8%) gap in the muscle cone, 14 patients (41.2%) located outside the muscle cone gap; 25 cases (73.5%) located in front of the eyes, in 6 cases (17.7%) eyes in the back, in 3 cases (8.8%) eyes front and rear are involved; 31 cases (91.2%) oval, 3 patients (8.8%) were round; 34 patients (100%) showed equal T1 T2 signal; 32 patients (94.1%) showed progressive enhancement, 2 patients (5.9%) non-uniform strengthening; 24 cases (70. 6%) TIC was out, 8 cases (23.5%) were platform type, 2 cases (5.9%) was sustained Enhanced. Compared with cavernous hemangioma, cavernous lymphangioma orbit in space outside the muscle cone more (p = 0. 03), occurred more frequently in women (p = 0. 03).

 Conclusion: Orbital cavernous lymphangioma cavernous hemangioma and MRI manifestations very similar, it is difficult to identify. If the orbital mass was oval or circular, etc. long T_2 T_1 signal and a "progressive enhancement" performance in the diagnosis and differential diagnosis should be considered when cavernous lymphangioma. Degree Year: 2009