Silicon amino compounds of rare earth catalytic Pudovik reaction

Title: Silicon amino compounds of rare earth catalytic Pudovik reaction
　　Author: Wu Qingmao
　　Degree awarded: Suzhou University
　　Keywords: amino rare-earth compounds of silicon;; Pudovik response;; α-hydroxy phosphonates;; catalysis;; synthesis;; D-mannitol;; chiral ligands;; oxazoline
　　Summary:
　　This thesis studied the catalytic synthesis of rare-earth compounds of silicon amino-α-hydroxy phosphonate reaction and D-mannitol derived chiral rare earth magnets ligands work. Specific content of the paper consists of two parts:
　　I. found that rare-earth compounds of silicon efficient catalytic amino aromatic aldehydes and dialkyl phosphite addition reaction (Pudovik reaction). Four-coordinated rare-earth compounds of silicon amino-[(Me_3Si) _2N] _3Ln (μ-Cl) Li (THF) _3 catalytic activity than three-coordinated silicon amino-earth compounds Ln [N (SiMe_3) _2] _3. At room temperature to 0.1 mol% [(Me_3Si) _2N] _3La (μ-Cl) Li (THF) _3 as a catalyst, 5 minutes to get close to the corresponding quantitative target compound α-hydroxy phosphonates. The effects of different reaction conditions, rare earth metals, alkali metals and halogen on the reactivity of the impact of proposed reaction mechanism, and speculated that the reason why the presence of LiCl greatly enhance the catalytic activity of the reasons.
　　Two. The source of wealth, C2 http://www.chinamagnets.biz/ symmetry of the D-mannitol as a chiral source, through condensation, nucleophilic substitution reactions, were synthesized D-mannitol derived diol compounds and oxazoline functional compounds with two chiral body, and preliminary exploration of the rare-earth compounds are amino-silicon reaction catalyzed Pudovik application.
　　Degree Year: 2010